INTRODUCTION
About Us
Research Areas
Main Research Areas of K-NIBRT's Biprocessing Training Center
Advanced Drug
Development and Smart cell Line Design
Development and Smart cell Line Design
Smart Bioprocessing Powered by
Digital Twin Technology
Digital Twin Technology
Bioproduct
Antibody & Protein Engineering
Biopharmaceutical Discovery and Design
- Antibody-Drug Conjugate (ABC) Technology
- Therapeutic antibody development
- Development of high-efficiency therapeutic targets
- Cell and gene therapy
Cell
Synthetic biology / metabolic engineering
Systemic strain development and cell processing
- vector design
- Gene therapy technology
- Genetic scissors technology
- systems biology
- Imaginary cell modeling
Data
Big Data & High-Efficiency Search Knowledge-Based Analysis and Monitoring Technologies
- (Online) Sensor Technology
- Big Data Analysis Technology
- Data Management
- Drug Screening Technology
Process
System Process Engineering
and Next-Generation Animal Cell Culture Technologies
- Animal Cell Culture Technology
- Process Control Technology
- Process Modularization and Simplification
- Continuous Manufacturing (CM)
01
Smart Bio Process Based on
Digital Twin Technology
- By combining continuous manufacturing (CM) technology and digital technology, this technology can perform predictive simulations for various culture conditions, optimize process conditions, and maximize biopharmaceutical production efficiency and quality.
02
Smart Cell Line
Design Technology
- The project is conducted in four areas: establishing a big database of animal-derived cells, developing machine learning techniques for gene targets, optimizing genome editing technologies for animal cells, and developing high-performacne animal cell production strains.
- Currently, the participating researchers and the NIBRT research team are jointly developing a single-cell analysis method for use in biopharmaceutical manufacturing process.
03
Advanced Biopharmaceutical (Gene/Cell Therapy)
Process Technology
- With the rapid rise of next-generation therapies such as gene and cell therapies, it is necessary to establish core base technologies for their development.
- We plan to build a genome-level metabolic model tailored for therapeutic cells and establish a digital twin-based production process that enables real-time monitoring of the cell culture process for cell therapies.
- We are currently working on a joint international research project with Singapore's BTI Research Institute to transfer technologies related to CART-T and stem culture processes.